Recent Publications
2024
- Identifying an Early Neuropathological Mechanism in Schizophrenia With Brain Organoids.Kim J, Park IH. Biol Psychiatry. 2024 Apr 1. PMID: 38479977.
- Combining physical & cognitive training with iPSC-derived dopaminergic neuron transplantation promotes graft integration & better functional outcome in parkinsonian marmosets.Daadi EW, Daadi ES, Oh T, Li M, Kim J, Daadi MM. Exp Neurol. 2024 Apr; 2024 Jan 23. PMID: 38272159.
- Human iPSC-Based Model of COPD to Investigate Disease Mechanisms, Predict SARS-COV-2 Outcome, and Test Preventive Immunotherapy.Dagher R, Moldobaeva A, Gubbins E, Clark S, Madel Alfajaro M, Wilen CB, Hawkins F, Qu X, Chien Chiang C, Li Y, Clarke L, Ikeda Y, Brown C, Kolbeck R, Ma Q, Rojas M, Koff JL, Ghaedi M. Stem Cells. 2024 Mar 14. PMID: 38183264.
- Wnt5 controls splenic myelopoiesis and neutrophil functional ambivalency during DSS-induced colitis.Luan Y, Hu J, Wang Q, Wang X, Li W, Qu R, Yang C, Rajendran BK, Zhou H, Liu P, Zhang N, Shi Y, Liu Y, Tang W, Lu J, Wu D. Cell Rep. 2024 Mar 8; 2024 Mar 8. PMID: 38461416.
- Author Correction: Subclonal cooperation drives metastasis by modulating local and systemic immune microenvironments.Janiszewska M, Tabassum DP, Castaño Z, Cristea S, Yamamoto KN, Kingston NL, Murphy KC, Shu S, Harper NW, Del Alcazar CG, Alečković M, Ekram MB, Cohen O, Kwak M, Qin Y, Laszewski T, Luoma A, Marusyk A, Wucherpfennig KW, Wagle N, Fan R, Michor F, McAllister SS, Polyak K. Nat Cell Biol. 2024 Mar 5; 2024 Mar 5. PMID: 38443568.
- Complementary and Inducible creER(T2) Mouse Models for Functional Evaluation of Endothelial Cell Subtypes in the Bone Marrow.Poulos MG, Ramalingam P, Winiarski A, Gutkin MC, Katsnelson L, Carter C, Pibouin-Fragner L, Eichmann A, Thomas JL, Miquerol L, Butler JM. Stem Cell Rev Rep. 2024 Mar 4; 2024 Mar 4. PMID: 38438768.
- The Epigenetic Evolution of Glioma Is Determined by the IDH1 Mutation Status and Treatment Regimen.Malta TM, Sabedot TS, Morosini NS, Datta I, Garofano L, Vallentgoed W, Varn FS, Aldape K, D'Angelo F, Bakas S, Barnholtz-Sloan JS, Gan HK, Hasanain M, Hau AC, Johnson KC, Cazacu S, deCarvalho AC, Khasraw M, Kocakavuk E, Kouwenhoven MCM, Migliozzi S, Niclou SP, Niers JM, Ormond DR, Paek SH, Reifenberger G, Sillevis Smitt PA, Smits M, Stead LF, van den Bent MJ, Van Meir EG, Walenkamp A, Weiss T, Weller M, Westerman BA, Ylstra B, Wesseling P, Lasorella A, French PJ, Poisson LM, Verhaak RGW, Iavarone A, Noushmehr H. Cancer Res. 2024 Mar 4. PMID: 38117484.
- Atypical pneumonia testing in transplant recipients.Feller F, Trubin P, Malinis M, Vogel JS, Merwede J, Peaper DR, Azar MM. Transpl Infect Dis. 2024 Mar 2; 2024 Mar 2. PMID: 38430482.
- Autophagy differentially regulates tissue tolerance of distinct target organs in graft-versus-host disease models.Oravecz-Wilson K, Lauder E, Taylor A, Maneix L, Van Nostrand JL, Sun Y, Li L, Zhao D, Liu C, Reddy P. J Clin Invest. 2024 Mar 1; 2024 Mar 1. PMID: 38426503.
- Circulating T cell specific extracellular vesicle profiles in cardiac allograft acute cellular rejection.Korutla L, Hoffman JR, Rostami S, Hu R, Korutla V, Markmann C, Mullan C, Sotolongo A, Habertheuer A, Romano C, Acker M, Sen S, Agarwal D, Jayaraman A, Li B, Davis ME, Naji A, Vallabhajosyula P. Am J Transplant. 2024 Mar; 2023 Oct 30. PMID: 38295008.
- HRAS-Mutant Cardiomyocyte Model of Multifocal Atrial Tachycardia.Rodríguez NA, Patel N, Dariolli R, Ng S, Aleman AG, Gong JQX, Lin HM, Rodríguez M, Josowitz R, Sol-Church K, Gripp KW, Lin X, Song SC, Fishman GI, Sobie EA, Gelb BD. Circ Arrhythm Electrophysiol. 2024 Feb 28; 2024 Feb 28. PMID: 38415356.
- Massively parallel disruption of enhancers active in human neural stem cells.Geller E, Noble MA, Morales M, Gockley J, Emera D, Uebbing S, Cotney JL, Noonan JP. Cell Rep. 2024 Feb 27; 2024 Jan 23. PMID: 38271204.
- The genomic and evolutionary landscapes of anaplastic thyroid carcinoma.Zeng PYF, Prokopec SD, Lai SY, Pinto N, Chan-Seng-Yue MA, Clifton-Bligh R, Williams MD, Howlett CJ, Plantinga P, Cecchini MJ, Lam AK, Siddiqui I, Wang J, Sun RX, Watson JD, Korah R, Carling T, Agrawal N, Cipriani N, Ball D, Nelkin B, Rooper LM, Bishop JA, Garnis C, Berean K, Nicolson NG, Weinberger P, Henderson YC, Lalansingh CM, Tian M, Yamaguchi TN, Livingstone J, Salcedo A, Patel K, Vizeacoumar F, Datti A, Xi L, Nikiforov YE, Smallridge R, Copland JA, Marlow LA, Hyrcza MD, Delbridge L, Sidhu S, Sywak M, Robinson B, Fung K, Ghasemi F, Kwan K, MacNeil SD, Mendez A, Palma DA, Khan MI, Shaikh M, Ruicci KM, Wehrli B, Winquist E, Yoo J, Mymryk JS, Rocco JW, Wheeler D, Scherer S, Giordano TJ, Barrett JW, Faquin WC, Gill AJ, Clayman G, Boutros PC, Nichols AC. Cell Rep. 2024 Feb 26; 2024 Feb 26. PMID: 38412093.
- The Wnt Co-Receptor PTK7/Otk and Its Homolog Otk-2 in Neurogenesis and Patterning.Tan QH, Otgonbaatar A, Kaur P, Ga AF, Harmston NP, Tolwinski NS. Cells. 2024 Feb 20; 2024 Feb 20. PMID: 38474329.
- Siponimod Attenuates Neuronal Cell Death Triggered by Neuroinflammation via NFκB and Mitochondrial Pathways.Gurrea-Rubio M, Wang Q, Mills EA, Wu Q, Pitt D, Tsou PS, Fox DA, Mao-Draayer Y. Int J Mol Sci. 2024 Feb 20; 2024 Feb 20. PMID: 38473703.
- Hypomethylating agents plus venetoclax compared with intensive induction chemotherapy regimens in molecularly defined secondary AML.Shimony S, Bewersdorf JP, Shallis RM, Liu Y, Schaefer EJ, Zeidan AM, Goldberg AD, Stein EM, Marcucci G, Lindsley RC, Chen EC, Ramos Perez J, Stein A, DeAngelo DJ, Neuberg DS, Stone RM, Ball B, Stahl M. Leukemia. 2024 Feb 20; 2024 Feb 20. PMID: 38378841.
- Activation of gp130 signaling in T cells drives T(H)17-mediated multi-organ autoimmunity.Baumgartner F, Bamopoulos SA, Faletti L, Hsiao HJ, Holz M, Gonzalez-Menendez I, Solé-Boldo L, Horne A, Gosavi S, Özerdem C, Singh N, Liebig S, Ramamoorthy S, Lehmann M, Demel U, Kühl AA, Wartewig T, Ruland J, Wunderlich FT, Schick M, Walther W, Rose-John S, Haas S, Quintanilla-Martinez L, Feske S, Ehl S, Glauben R, Keller U. Sci Signal. 2024 Feb 20; 2024 Feb 20. PMID: 38377177.
- Characterization of enhancer activity in early human neurodevelopment using Massively Parallel Reporter Assay (MPRA) and forebrain organoids.Capauto D, Wang Y, Wu F, Norton S, Mariani J, Inoue F, Crawford GE, Ahituv N, Abyzov A, Vaccarino FM. Sci Rep. 2024 Feb 16; 2024 Feb 16. PMID: 38365907.
- Immune-restoring CAR-T cells display antitumor activity and reverse immunosuppressive TME in a humanized ccRCC mouse model.Wang Y, Cho JW, Kastrunes G, Buck A, Razimbaud C, Culhane AC, Sun J, Braun DA, Choueiri TK, Wu CJ, Jones K, Nguyen QD, Zhu Z, Wei K, Zhu Q, Signoretti S, Freeman GJ, Hemberg M, Marasco WA. iScience. 2024 Feb 16; 2024 Jan 15. PMID: 38327771.
- Resilient wings, tangible impact: My journey from chrysalis to changemaker in STEM.Wilson JA. Cell. 2024 Feb 15. PMID: 38364786.
- Cell surface RNAs control neutrophil recruitment.Zhang N, Tang W, Torres L, Wang X, Ajaj Y, Zhu L, Luan Y, Zhou H, Wang Y, Zhang D, Kurbatov V, Khan SA, Kumar P, Hidalgo A, Wu D, Lu J. Cell. 2024 Feb 15; 2024 Jan 22. PMID: 38262409.
- Rehabilitation facilitates functional improvement following intravenous infusion of mesenchymal stem cells in the chronic phase of cerebral ischemia in rats.Yamashita T, Sasaki M, Sasaki Y, Nagahama H, Oka S, Kataoka-Sasaki Y, Ukai R, Yokoyama T, Kobayashi M, Kakizawa M, Kocsis JD, Honmou O. Brain Res. 2024 Feb 15; 2023 Dec 10. PMID: 38072373.
- Stem cell migration drives lung repair in living mice.Chioccioli M, Liu S, Magruder S, Tata A, Borriello L, McDonough JE, Konkimalla A, Kim SH, Nouws J, Gonzalez DG, Traub B, Ye X, Yang T, Entenberg DR, Krishnaswamy S, Hendry CE, Kaminski N, Tata PR, Sauler M. Dev Cell. 2024 Feb 14; 2024 Feb 14. PMID: 38377991.
- Evidence for C-peptide as a Validated Surrogate to Predict Clinical Benefits in Trials of Disease-Modifying Therapies for Type 1 Diabetes.Latres E, Greenbaum CJ, Oyaski ML, Dayan CM, Colhoun HM, Lachin JM, Skyler JS, Rickels MR, Ahmed ST, Dutta S, Herold KC, Marinac M. Diabetes. 2024 Feb 13; 2024 Feb 13. PMID: 38349844.
- Corticosteroids impair epithelial regeneration in immune-mediated intestinal damage.Arnhold V, Chang WY, Jansen SA, Thangavelu G, Calafiore M, Vinci P, Fu YY, Ito T, Takashima S, Egorova A, Kuttiyara J, Perlstein A, van Hoesel M, Liu C, Blazar BR, Lindemans CA, Hanash AM. J Clin Invest. 2024 Feb 13; 2024 Feb 13. PMID: 38349762.
- Current state of the epilepsy drug and device pipeline.Terman SW, Kirkpatrick L, Akiyama LF, Baajour W, Atilgan D, Dorotan MKC, Choi HW, French JA. Epilepsia. 2024 Feb 12; 2024 Feb 12. PMID: 38345387.
- Fluoride transport in Arabidopsis thaliana plants is impaired in Fluoride EXporter (FEX) mutants.Tausta SL, Fontaine K, Hillmer AT, Strobel SA. Plant Mol Biol. 2024 Feb 11; 2024 Feb 11. PMID: 38342783.
- Real-World Survival, Healthcare Resource Utilization, and Costs Among U.S. Elderly Patients With Diffuse Large B-Cell Lymphoma (DLBCL) Treated With R-GemOx in the Relapsed/Refractory Setting.Garg M, Puckett J, Kamal-Bahl S, Raut M, Ryland KE, Doshi JA, Huntington SF. Clin Lymphoma Myeloma Leuk. 2024 Feb 9; 2024 Feb 9. PMID: 38433043.
- Spatially Exploring RNA Biology in Archival Formalin-Fixed Paraffin-Embedded Tissues.Bai Z, Zhang D, Gao Y, Tao B, Bao S, Enninful A, Zhang D, Su G, Tian X, Zhang N, Xiao Y, Liu Y, Gerstein M, Li M, Xing Y, Lu J, Xu ML, Fan R. bioRxiv. 2024 Feb 8; 2024 Feb 8. PMID: 38370833.
- IDHwt glioblastomas can be stratified by their transcriptional response to standard treatment, with implications for targeted therapy.Tanner G, Barrow R, Ajaib S, Al-Jabri M, Ahmed N, Pollock S, Finetti M, Rippaus N, Bruns AF, Syed K, Poulter JA, Matthews L, Hughes T, Wilson E, Johnson C, Varn FS, Brüning-Richardson A, Hogg C, Droop A, Gusnanto A, Care MA, Cutillo L, Westhead DR, Short SC, Jenkinson MD, Brodbelt A, Chakrabarty A, Ismail A, Verhaak RGW, Stead LF. Genome Biol. 2024 Feb 7; 2024 Feb 7. PMID: 38326875.
- Longitudinal single-cell transcriptional dynamics throughout neurodegeneration in SCA1.Tejwani L, Ravindra NG, Lee C, Cheng Y, Nguyen B, Luttik K, Ni L, Zhang S, Morrison LM, Gionco J, Xiang Y, Yoon J, Ro H, Haidery F, Grijalva RM, Bae E, Kim K, Martuscello RT, Orr HT, Zoghbi HY, McLoughlin HS, Ranum LPW, Shakkottai VG, Faust PL, Wang S, van Dijk D, Lim J. Neuron. 2024 Feb 7; 2023 Nov 27. PMID: 38016472.
- The conserved RNA-binding protein Imp is required for the specification and function of olfactory navigation circuitry in Drosophila.Hamid A, Gattuso H, Caglar AN, Pillai M, Steele T, Gonzalez A, Nagel K, Syed MH. Curr Biol. 2024 Feb 5; 2024 Jan 4. PMID: 38181792.
- Autonomous transposons tune their sequences to ensure somatic suppression.Ilık İA, Glažar P, Tse K, Brändl B, Meierhofer D, Müller FJ, Smith ZD, Aktaş T. Nature. 2024 Feb; 2024 Feb 14. PMID: 38355802.
- Modulation of canonical Wnt signaling regulates peribiliary mesenchymal identity during homeostasis and injury.Singh S, Budiman T, Redmond D, Gupta V. Hepatol Commun. 2024 Feb 1; 2024 Jan 22. PMID: 38251878.
- Insertion of a FLAG-tag sequence at the end of exon 9 of the TBX5 gene in three induced pluripotent stem cell lines (DHMi004-A-4, DHMi004-A-5, DHMi004-A-6) by CRISPR/Cas9 technology.Lahm H, Singh NK, Gottmann I, Doppler SA, Dzilic E, Preisler H, Schneider S, Lange R, Krane M, Dreßen M. Stem Cell Res. 2024 Feb; 2023 Nov 25. PMID: 38100916.
- Modelling post-implantation human development to yolk sac blood emergence.Hislop J, Song Q, Keshavarz F K, Alavi A, Schoenberger R, LeGraw R, Velazquez JJ, Mokhtari T, Taheri MN, Rytel M, Chuva de Sousa Lopes SM, Watkins S, Stolz D, Kiani S, Sozen B, Bar-Joseph Z, Ebrahimkhani MR. Nature. 2024 Feb; 2023 Dec 13. PMID: 38092041.
- AAV-mediated delivery of a Sleeping Beauty transposon and an mRNA-encoded transposase for the engineering of therapeutic immune cells.Ye L, Lam SZ, Yang L, Suzuki K, Zou Y, Lin Q, Zhang Y, Clark P, Peng L, Chen S. Nat Biomed Eng. 2024 Feb; 2023 Jul 10. PMID: 37430157.
- The cholesterol biosynthesis enzyme FAXDC2 couples Wnt/β-catenin to RTK/MAPK signaling.Madan B, Wadia SR, Patnaik S, Harmston N, Tan E, Tan IBH, Nes WD, Petretto E, Virshup DM. J Clin Invest. 2024 Jan 23; 2024 Jan 23. PMID: 38488003.
- Regulation of nuclear transcription by mitochondrial RNA in endothelial cells.Sriram K, Qi Z, Yuan D, Malhi NK, Liu X, Calandrelli R, Luo Y, Tapia A, Jin S, Shi J, Salas M, Dang R, Armstrong B, Priceman SJ, Wang PH, Liao J, Natarajan R, Zhong S, Bouman Chen Z. Elife. 2024 Jan 22; 2024 Jan 22. PMID: 38251974.
- Presenilin-1 in smooth muscle cells facilitates hypermuscularization in elastin aortopathy.Saito J, Dave JM, Lau FD, Greif DM. iScience. 2024 Jan 19; 2023 Dec 13. PMID: 38226162.
- Antitumor efficacy of a sequence-specific DNA-targeted γPNA-based c-Myc inhibitor.Malik S, Pradeep SP, Kumar V, Xiao Y, Deng Y, Fan R, Vasquez JC, Singh V, Bahal R. Cell Rep Med. 2024 Jan 16; 2024 Jan 5. PMID: 38183981.
- Genome scale CRISPR screens identify actin capping proteins as key modulators of therapeutic responses to radiation and immunotherapy.Verma N, Renauer PA, Dong C, Xin S, Lin Q, Zhang F, Glazer PM, Chen S. bioRxiv. 2024 Jan 15; 2024 Jan 15. PMID: 38293095.
- Transitions in development - an interview with Berna Sozen.Development. 2024 Jan 15; 2024 Jan 17. PMID: 38231011.
- Activity-Dependent Transcriptional Program in NGN2+ Neurons Enriched for Genetic Risk for Brain-Related Disorders.Ma Y, Bendl J, Hartley BJ, Fullard JF, Abdelaal R, Ho SM, Kosoy R, Gochman P, Rapoport J, Hoffman GE, Brennand KJ, Roussos P. Biol Psychiatry. 2024 Jan 15; 2023 Jul 14. PMID: 37454787.
- Organ Boundary Circuits Regulate Sox9+ Alveolar Tuft Cells During Post-Pneumonectomy Lung Regeneration.Obata T, Mizoguchi S, Greaney AM, Adams T, Yuan Y, Edelstein S, Leiby KL, Rivero R, Wang N, Kim H, Yang J, Schupp JC, Stitelman D, Tsuchiya T, Levchenko A, Kaminski N, Niklason LE, Brickman Raredon MS. bioRxiv. 2024 Jan 8; 2024 Jan 8. PMID: 38260691.
- Dysregulation of alternative splicing in spinocerebellar ataxia type 1.Olmos V, Thompson EN, Gogia N, Luttik K, Veeranki V, Ni L, Sim S, Chen K, Krause DS, Lim J. Hum Mol Genet. 2024 Jan 7. PMID: 37802886.
- Paneth-like cells produced from OLFM4(+) stem cells support OLFM4(+) stem cell growth in advanced colorectal cancer.Sakahara M, Okamoto T, Srivastava U, Natsume Y, Yamanaka H, Suzuki Y, Obama K, Nagayama S, Yao R. Commun Biol. 2024 Jan 5; 2024 Jan 5. PMID: 38182890.
- Proteogenomic characterization of small cell lung cancer identifies biological insights and subtype-specific therapeutic strategies.Liu Q, Zhang J, Guo C, Wang M, Wang C, Yan Y, Sun L, Wang D, Zhang L, Yu H, Hou L, Wu C, Zhu Y, Jiang G, Zhu H, Zhou Y, Fang S, Zhang T, Hu L, Li J, Liu Y, Zhang H, Zhang B, Ding L, Robles AI, Rodriguez H, Gao D, Ji H, Zhou H, Zhang P. Cell. 2024 Jan 4. PMID: 38181741.
- Allogeneic transplantation and cellular therapies in cutaneous T-cell lymphoma.Goyal A, Foss F. Expert Rev Anticancer Ther. 2024 Jan-Feb; 2024 Feb 12. PMID: 38224371.
- Extent of resection for low-grade gliomas - Prognostic or therapeutic?Kinslow CJ, Garton ALA, Rae AI, Kocakavuk E, McKhann GM, Cheng SK, Sisti MB, Bruce JN, Wang TJC. Clin Neurol Neurosurg. 2024 Jan; 2024 Jan 9. PMID: 38219356.
- Immune Control in Repeated Babesia microti Infection in a Patient With B-Cell Deficiency.Little JS, Oakley MS, Thorner AR, Johnston D, Majam V, Liakos AD, Novack LA, Zheng H, Meredith S, Chou CK, Newton BR, Soiffer RJ, Krause PJ, Baden LR, Kumar S. Open Forum Infect Dis. 2024 Jan; 2023 Nov 13. PMID: 38213635.
- Author Correction: Apoptotic stress causes mtDNA release during senescence and drives the SASP.Victorelli S, Salmonowicz H, Chapman J, Martini H, Vizioli MG, Riley JS, Cloix C, Hall-Younger E, Machado Espindola-Netto J, Jurk D, Lagnado AB, Sales Gomez L, Farr JN, Saul D, Reed R, Kelly G, Eppard M, Greaves LC, Dou Z, Pirius N, Szczepanowska K, Porritt RA, Huang H, Huang TY, Mann DA, Masuda CA, Khosla S, Dai H, Kaufmann SH, Zacharioudakis E, Gavathiotis E, LeBrasseur NK, Lei X, Sainz AG, Korolchuk VI, Adams PD, Shadel GS, Tait SWG, Passos JF. Nature. 2024 Jan. PMID: 38168624.
- 3D hepatic organoid production from human pluripotent stem cells.Jin ZL, Xu K, Kim J, Guo H, Yao X, Xu YN, Li YH, Ryu D, Kim KP, Hong K, Kim YJ, Wang L, Cao Q, Kim KH, Kim NH, Han DW. Differentiation. 2024 Jan-Feb; 2023 Dec 12. PMID: 38104501.
- Sabatolimab plus hypomethylating agents in previously untreated patients with higher-risk myelodysplastic syndromes (STIMULUS-MDS1): a randomised, double-blind, placebo-controlled, phase 2 trial.Zeidan AM, Ando K, Rauzy O, Turgut M, Wang MC, Cairoli R, Hou HA, Kwong YL, Arnan M, Meers S, Pullarkat V, Santini V, Malek K, Kiertsman F, Niolat J, Ramos PM, Menssen HD, Fenaux P, Miyazaki Y, Platzbecker U. Lancet Haematol. 2024 Jan; 2023 Dec 5. PMID: 38065203.
- Identification of constrained sequence elements across 239 primate genomes.Kuderna LFK, Ulirsch JC, Rashid S, Ameen M, Sundaram L, Hickey G, Cox AJ, Gao H, Kumar A, Aguet F, Christmas MJ, Clawson H, Haeussler M, Janiak MC, Kuhlwilm M, Orkin JD, Bataillon T, Manu S, Valenzuela A, Bergman J, Rouselle M, Silva FE, Agueda L, Blanc J, Gut M, de Vries D, Goodhead I, Harris RA, Raveendran M, Jensen A, Chuma IS, Horvath JE, Hvilsom C, Juan D, Frandsen P, Schraiber JG, de Melo FR, Bertuol F, Byrne H, Sampaio I, Farias I, Valsecchi J, Messias M, da Silva MNF, Trivedi M, Rossi R, Hrbek T, Andriaholinirina N, Rabarivola CJ, Zaramody A, Jolly CJ, Phillips-Conroy J, Wilkerson G, Abee C, Simmons JH, Fernandez-Duque E, Kanthaswamy S, Shiferaw F, Wu D, Zhou L, Shao Y, Zhang G, Keyyu JD, Knauf S, Le MD, Lizano E, Merker S, Navarro A, Nadler T, Khor CC, Lee J, Tan P, Lim WK, Kitchener AC, Zinner D, Gut I, Melin AD, Guschanski K, Schierup MH, Beck RMD, Karakikes I, Wang KC, Umapathy G, Roos C, Boubli JP, Siepel A, Kundaje A, Paten B, Lindblad-Toh K, Rogers J, Marques Bonet T, Farh KK. Nature. 2024 Jan; 2023 Nov 29. PMID: 38030727.
- Phenotypic and proteomic characterization of the human erythroid progenitor continuum reveal dynamic changes in cell cycle and in metabolic pathways.Papoin J, Yan H, Leduc M, Le Gall M, Narla A, Palis J, Steiner LA, Gallagher PG, Hillyer CD, Gautier EF, Mohandas N, Blanc L. Am J Hematol. 2024 Jan; 2023 Nov 6. PMID: 37929634.
- Post-transplantation cyclophosphamide is associated with increased bacterial infections.Ustun C, Chen M, Kim S, Auletta JJ, Batista MV, Battiwalla M, Cerny J, Gowda L, Hill JA, Liu H, Munshi PN, Nathan S, Seftel MD, Wingard JR, Chemaly RF, Dandoy CE, Perales MA, Riches M, Papanicolaou GA. Bone Marrow Transplant. 2024 Jan; 2023 Oct 31. PMID: 37903992.
- Allogeneic stem cell transplant for treatment of mycosis fungoides and Sezary syndrome: a systematic review and meta-analysis.Goyal A, O'Leary D, Foss F. Bone Marrow Transplant. 2024 Jan; 2023 Oct 18. PMID: 37853164.
- Safety of ovarian cryopreservation and transplantation in patients with acute leukemia: a case series.Sönmezer M, Şükür YE, Saçıntı KG, Özkavukçu S, Kankaya D, Atabekoğlu CS, Cengiz Seval G, Oktay KH. Am J Obstet Gynecol. 2024 Jan; 2023 Sep 2. PMID: 37666382.
- Bioinformatics identifies predictors of arteriovenous fistula maturation.Liu J, Zhang D, Brahmandam A, Matsubara Y, Gao M, Tian J, Liu B, Shu C, Dardik A. J Vasc Access. 2024 Jan; 2022 Jun 10. PMID: 35686495.
2023
- IL-10 dampens antitumor immunity and promotes liver metastasis via PD-L1 induction.Shiri AM, Zhang T, Bedke T, Zazara DE, Zhao L, Lücke J, Sabihi M, Fazio A, Zhang S, Tauriello DVF, Batlle E, Steglich B, Kempski J, Agalioti T, Nawrocki M, Xu Y, Riecken K, Liebold I, Brockmann L, Konczalla L, Bosurgi L, Mercanoglu B, Seeger P, Küsters N, Lykoudis PM, Heumann A, Arck PC, Fehse B, Busch P, Grotelüschen R, Mann O, Izbicki JR, Hackert T, Flavell RA, Gagliani N, Giannou AD, Huber S. J Hepatol. 2023 Dec 30; 2023 Dec 30. PMID: 38160941.
- Evidence for Functional Roles of MicroRNAs in Lineage Specification During Mouse and Human Preimplantation Development.Biondic S, Petropoulos S. Yale J Biol Med. 2023 Dec; 2023 Dec 29. PMID: 38161584.
- The Molecular Mechanisms Involved in the Hypertrophic Scars Post-Burn Injury.Pradhan M, Pethe P. Yale J Biol Med. 2023 Dec; 2023 Dec 29. PMID: 38161582.
- Enhancing Our Understanding of Cell Types, Differentiation, and Disease Through Enhancers: An Interview with César Daniel Meléndez-Ramírez, MS.Abu-Shamma R. Yale J Biol Med. 2023 Dec; 2023 Dec 29. PMID: 38161574.
- Differences in syncytia formation by SARS-CoV-2 variants modify host chromatin accessibility and cellular senescence via TP53.Lee JD, Menasche BL, Mavrikaki M, Uyemura MM, Hong SM, Kozlova N, Wei J, Alfajaro MM, Filler RB, Müller A, Saxena T, Posey RR, Cheung P, Muranen T, Heng YJ, Paulo JA, Wilen CB, Slack FJ. Cell Rep. 2023 Dec 26; 2023 Nov 21. PMID: 37991919.
- piRNA generation is associated with the pioneer round of translation in stem cells.Allikka Parambil S, Li D, Zelko M, Poulet A, van Wolfswinkel JC. Nucleic Acids Res. 2023 Dec 24; 2023 Dec 24. PMID: 38142432.
- Precise Therapeutic Targeting of Distinct NRXN1(+/-) Mutations.Fernando MB, Fan Y, Zhang Y, Kammourh S, Murphy AN, Ghorbani S, Onatzevitch R, Pero A, Padilla C, Flaherty EK, Prytkova IK, Cao L, Williams S, Fang G, Slesinger PA, Brennand KJ. bioRxiv. 2023 Dec 23; 2023 Dec 23. PMID: 37961635.
- A novel SMARCC1 BAFopathy implicates neural progenitor epigenetic dysregulation in human hydrocephalus.Singh AK, Allington G, Viviano S, McGee S, Kiziltug E, Ma S, Zhao S, Mekbib KY, Shohfi JP, Duy PQ, DeSpenza T Jr, Furey CG, Reeves BC, Smith H, Sousa AMM, Cherskov A, Allocco A, Nelson-Williams C, Haider S, Rizvi SRA, Alper SL, Sestan N, Shimelis H, Walsh LK, Lifton RP, Moreno-De-Luca A, Jin SC, Kruszka P, Deniz E, Kahle KT. Brain. 2023 Dec 21; 2023 Dec 21. PMID: 38128548.
- Genome Engineering for Next-Generation Cellular Immunotherapies.Park JJ, Lee KAV, Lam SZ, Tang K, Chen S. Biochemistry. 2023 Dec 19; 2022 Aug 5. PMID: 35930700.
- Macrophages control pathological interferon responses during viral respiratory infection.Hoagland DA, Rodríguez-Morales P, Mann AO, Yu S, Lai A, Vazquez AB, Pope SD, Lim J, Li S, Zhang X, Li MO, Medzhitov R, Franklin RA. bioRxiv. 2023 Dec 17; 2023 Dec 17. PMID: 38168230.
- Diencephalic organoids - A key to unraveling development, connectivity, and pathology of the human diencephalon.Kiral FR, Choe M, Park IH. Front Cell Neurosci. 2023; 2023 Dec 7. PMID: 38130869.
- Trellis tree-based analysis reveals stromal regulation of patient-derived organoid drug responses.Ramos Zapatero M, Tong A, Opzoomer JW, O'Sullivan R, Cardoso Rodriguez F, Sufi J, Vlckova P, Nattress C, Qin X, Claus J, Hochhauser D, Krishnaswamy S, Tape CJ. Cell. 2023 Dec 7. PMID: 38065081.
- Trained immunity induced by high-salt diet impedes stroke recovery.Lin TY, Jiang D, Chen WR, Lin JS, Zhang XY, Chen CH, Hsu CL, Lai LC, Chen PH, Yang KC, Sansing LH, Chang CF. EMBO Rep. 2023 Dec 6; 2023 Nov 15. PMID: 37965920.
- Heterogeneous murine peribiliary glands orchestrate compartmentalized epithelial renewal.Singh S, Lian Q, Budiman T, Taketo MM, Simons BD, Gupta V. Dev Cell. 2023 Dec 4; 2023 Oct 30. PMID: 37909044.
- Pooled screening with next-generation gene editing tools.Zhou L, Yang L, Feng Y, Chen S. Curr Opin Biomed Eng. 2023 Dec; 2023 Jun 21. PMID: 38222973.
- Extensive Intracardiac Cement Embolism in a Patient Undergoing Workup for Bone Marrow Transplant.Waidyaratne G, Bennett C, Umyarova E, Bumma N. J Hematol. 2023 Dec; 2023 Dec 9. PMID: 38188473.
- The H2Bub1-deposition complex is required for human and mouse cardiogenesis.Barish S, Berg K, Drozd J, Berglund-Brown I, Khizir L, Wasson LK, Seidman CE, Seidman JG, Chen S, Brueckner M. Development. 2023 Dec 1; 2023 Dec 1. PMID: 38038666.
- Onconephrology: Core Curriculum 2023.Yarandi N, Shirali AC. Am J Kidney Dis. 2023 Dec; 2023 Oct 17. PMID: 37855786.
- Young EFIS: Three years of progress - Reflecting on achievements and embracing new horizons.Glymenaki M, Hahn AM, Hausmann A, Kempkes RWM, Kilic G, Kulsvehagen L, Mooslechner AA, Mossadegh-Keller N, Nabhan M, Bechara R. Eur J Immunol. 2023 Dec; 2023 Oct 20. PMID: 37751329.
- Bleeding in Critically Ill Children With Malignancy or Hematopoietic Cell Transplant: A Single-Center Prospective Cohort Study.Levasseur J, Fikse L, Mauguen A, Killinger JS, Karam O, Nellis ME. Pediatr Crit Care Med. 2023 Dec 1; 2023 Sep 7. PMID: 37678406.
- Therapeutic efficacy of intravenous infusion of mesenchymal stem cells in rat perinatal brain injury.Terada K, Sasaki M, Nagahama H, Kataoka-Sasaki Y, Oka S, Ukai R, Yokoyama T, Iizuka Y, Sakai T, Fukumura S, Tsugawa T, Kocsis JD, Honmou O. Pediatr Res. 2023 Dec; 2023 Jul 8. PMID: 37422495.
- Epicardioid single-cell genomics uncovers principles of human epicardium biology in heart development and disease.Meier AB, Zawada D, De Angelis MT, Martens LD, Santamaria G, Zengerle S, Nowak-Imialek M, Kornherr J, Zhang F, Tian Q, Wolf CM, Kupatt C, Sahara M, Lipp P, Theis FJ, Gagneur J, Goedel A, Laugwitz KL, Dorn T, Moretti A. Nat Biotechnol. 2023 Dec; 2023 Apr 3. PMID: 37012447.
- Simultaneous transfer of one good-quality and one poor-quality cleavage stage embryo does not improve pregnancy outcomes.Liu J, Kumar I, Li T, Ding Y, Tian Q, Tang X, Huang X, Hu W, Liu Y, Wang Z. Hum Fertil (Camb). 2023 Dec; 2022 Nov 15. PMID: 36380565.
- Pulmonary microbiome and transcriptome signatures reveal distinct pathobiologic states associated with mortality in two cohorts of pediatric stem cell transplant patients.Zinter MS, Dvorak CC, Mayday MY, Reyes G, Simon MR, Pearce EM, Kim H, Shaw PJ, Rowan CM, Auletta JJ, Martin PL, Godder K, Duncan CN, Lalefar NR, Kreml EM, Hume JR, Abdel-Azim H, Hurley C, Cuvelier GDE, Keating AK, Qayed M, Killinger JS, Fitzgerald JC, Hanna R, Mahadeo KM, Quigg TC, Satwani P, Castillo P, Gertz SJ, Moore TB, Hanisch B, Abdel-Mageed A, Phelan R, Davis DB, Hudspeth MP, Yanik GA, Pulsipher MA, Sulaiman I, Segal LN, Versluys BA, Lindemans CA, Boelens JJ, DeRisi JL. medRxiv. 2023 Nov 29; 2023 Nov 29. PMID: 38077035.
- Allogeneic hematopoietic cell transplantation for blastic plasmacytoid dendritic cell neoplasm: a CIBMTR analysis.Murthy HS, Zhang MJ, Chen K, Ahmed S, Deotare U, Ganguly S, Kansagra A, Michelis FV, Nishihori T, Patnaik M, Abid MB, Aljurf M, Arai Y, Bacher U, Badar T, Badawy SM, Ballen K, Battiwalla M, Beitinjaneh A, Bejanyan N, Bhatt VR, Brown VI, Martino R, Cahn JY, Castillo P, Cerny J, Chhabra S, Copelan E, Daly A, Dholaria B, Diaz Perez MA, Freytes CO, Grunwald MR, Hashmi S, Hildebrandt GC, Jamy O, Joseph J, Kanakry CG, Khera N, Krem MM, Kuwatsuka Y, Lazarus HM, Lekakis LJ, Liu H, Modi D, Munshi PN, Mussetti A, Palmisiano N, Patel SS, Rizzieri DA, Seo S, Shah MV, Sharma A, Sohl M, Solomon SR, Ulrickson M, Ustun C, van der Poel M, Verdonck LF, Wagner JL, Wang T, Wirk B, Zeidan A, Litzow M, Kebriaei P, Hourigan CS, Weisdorf DJ, Saber W, Kharfan-Dabaja MA. Blood Adv. 2023 Nov 28. PMID: 37792849.
- Elevated CDKN1A (P21) mediates β-thalassemia erythroid apoptosis, but its loss does not improve β-thalassemic erythropoiesis.Liang R, Lin M, Menon V, Qiu J, Menon A, Breda L, Arif T, Rivella S, Ghaffari S. Blood Adv. 2023 Nov 28. PMID: 37672319.
- Mitochondrial leak metabolism induces the Spemann-Mangold Organizer via Hif-1α in Xenopus.MacColl Garfinkel A, Mnatsakanyan N, Patel JH, Wills AE, Shteyman A, Smith PJS, Alavian KN, Jonas EA, Khokha MK. Dev Cell. 2023 Nov 20; 2023 Sep 5. PMID: 37673063.
- High-grade B-cell lymphoma, not otherwise specified: a multi-institutional retrospective study.Zayac AS, Landsburg DJ, Hughes ME, Bock AM, Nowakowski GS, Ayers EC, Girton M, Hu M, Beckman AK, Li S, Medeiros LJ, Chang JE, Stepanovic A, Kurt H, Sandoval-Sus J, Ansari-Lari MA, Kothari SK, Kress A, Xu ML, Torka P, Sundaram S, Smith SD, Naresh KN, Karimi YH, Epperla N, Bond DA, Farooq U, Saad M, Evens AM, Pandya K, Naik SG, Kamdar M, Haverkos B, Karmali R, Oh TS, Vose JM, Nutsch H, Rubinstein PG, Chaudhry A, Olszewski AJ. Blood Adv. 2023 Nov 14. PMID: 37171397.
- Immunological and clinicopathological features predict HER2-positive breast cancer prognosis in the neoadjuvant NeoALTTO and CALGB 40601 randomized trials.Rediti M, Fernandez-Martinez A, Venet D, Rothé F, Hoadley KA, Parker JS, Singh B, Campbell JD, Ballman KV, Hillman DW, Winer EP, El-Abed S, Piccart M, Di Cosimo S, Symmans WF, Krop IE, Salgado R, Loi S, Pusztai L, Perou CM, Carey LA, Sotiriou C. Nat Commun. 2023 Nov 3; 2023 Nov 3. PMID: 37923752.
- Distinct clinical phenotypes in paediatric cancer patients with sepsis are associated with different outcomes-an international multicentre retrospective study.Wösten-van Asperen RM, la Roi-Teeuw HM, van Amstel RB, Bos LD, Tissing WJ, Jordan I, Dohna-Schwake C, Bottari G, Pappachan J, Crazzolara R, Comoretto RI, Mizia-Malarz A, Moscatelli A, Sánchez-Martín M, Willems J, Rogerson CM, Bennett TD, Luo Y, Atreya MR, Faustino EVS, Geva A, Weiss SL, Schlapbach LJ, Sanchez-Pinto LN. EClinicalMedicine. 2023 Nov; 2023 Oct 5. PMID: 37842550.
- Remission of severe myasthenia gravis after autologous stem cell transplantation.Schlatter MI, Yandamuri SS, O'Connor KC, Nowak RJ, Pham MC, Obaid AH, Redman C, Provost M, McSweeney PA, Pearlman ML, Tees MT, Bowen JD, Nash RA, Georges GE. Ann Clin Transl Neurol. 2023 Nov; 2023 Sep 19. PMID: 37726935.
- Classification, risk stratification and response assessment in myelodysplastic syndromes/neoplasms (MDS): A state-of-the-art report on behalf of the International Consortium for MDS (icMDS).Stahl M, Bewersdorf JP, Xie Z, Porta MGD, Komrokji R, Xu ML, Abdel-Wahab O, Taylor J, Steensma DP, Starczynowski DT, Sekeres MA, Sanz G, Sallman DA, Roboz GJ, Platzbecker U, Patnaik MM, Padron E, Odenike O, Nimer SD, Nazha A, Majeti R, Loghavi S, Little RF, List AF, Kim TK, Hourigan CS, Hasserjian RP, Halene S, Griffiths EA, Gore SD, Greenberg P, Figueroa ME, Fenaux P, Efficace F, DeZern AE, Daver NG, Churpek JE, Carraway HE, Buckstein R, Brunner AM, Boultwood J, Borate U, Bejar R, Bennett JM, Wei AH, Santini V, Savona MR, Zeidan AM. Blood Rev. 2023 Nov; 2023 Aug 19. PMID: 37704469.
- Nutrient regulation of bone marrow adipose tissue: skeletal implications of weight loss.Rosen CJ, Horowitz MC. Nat Rev Endocrinol. 2023 Nov; 2023 Aug 16. PMID: 37587198.
- Racial and Socioeconomic Disparities in Long-Term Outcomes in ≥1 Year Allogeneic Hematopoietic Cell Transplantation Survivors: A CIBMTR Analysis.Blue BJ, Brazauskas R, Chen K, Patel J, Zeidan AM, Steinberg A, Ballen K, Kwok J, Rotz SJ, Perez MAD, Kelkar AH, Ganguly S, Wingard JR, Lad D, Sharma A, Badawy SM, Lazarus HM, Hashem H, Szwajcer D, Knight JM, Bhatt NS, Page K, Beattie S, Arai Y, Liu H, Arnold SD, Freytes CO, Abid MB, Beitinjaneh A, Farhadfar N, Wirk B, Winestone LE, Agrawal V, Preussler JM, Seo S, Hashmi S, Lehmann L, Wood WA, Rangarajan HG, Saber W, Majhail NS. Transplant Cell Ther. 2023 Nov; 2023 Jul 22. PMID: 37482244.
- Applications of CRISPR technology in cellular immunotherapy.Zhou X, Renauer PA, Zhou L, Fang SY, Chen S. Immunol Rev. 2023 Nov; 2023 Jul 14. PMID: 37449673.
- Interrater reproducibility of the Myoton and durometer devices to quantify sclerotic chronic graft-versus-host disease.Ghosh S, Baker L, Chen F, Khera Z, Vain A, Zhang K, Hood A, Smith H, Chen H, Jagasia M, Tkaczyk E. Arch Dermatol Res. 2023 Nov; 2023 May 25. PMID: 37227518.
- Innovations in Stem Cell Therapy for Diabetic Wound Healing.Ho J, Yue D, Cheema U, Hsia HC, Dardik A. Adv Wound Care (New Rochelle). 2023 Nov; 2022 Apr 19. PMID: 35176896.
- Negative feedback regulation of MAPK signaling is an important driver of chronic lymphocytic leukemia progression.Ecker V, Brandmeier L, Stumpf M, Giansanti P, Moreira AV, Pfeuffer L, Fens MHAM, Lu J, Kuster B, Engleitner T, Heidegger S, Rad R, Ringshausen I, Zenz T, Wendtner CM, Müschen M, Jellusova J, Ruland J, Buchner M. Cell Rep. 2023 Oct 31; 2023 Oct 4. PMID: 37792532.
- ALKBH5 modulates hematopoietic stem and progenitor cell energy metabolism through m(6)A modification-mediated RNA stability control.Gao Y, Zimmer JT, Vasic R, Liu C, Gbyli R, Zheng SJ, Patel A, Liu W, Qi Z, Li Y, Nelakanti R, Song Y, Biancon G, Xiao AZ, Slavoff S, Kibbey RG, Flavell RA, Simon MD, Tebaldi T, Li HB, Halene S. Cell Rep. 2023 Oct 31; 2023 Sep 23. PMID: 37742191.
- IDR-induced CAR condensation improves the cytotoxicity of CAR-Ts against low-antigen cancers.Zhang X, Xiao Q, Zeng L, Hashmi F, Su X. bioRxiv. 2023 Oct 28; 2023 Oct 28. PMID: 37873222.