The Xiao Lab focuses on characterizing unique cellular and molecular features of pluripotent stem cells (PSCs) and the underlying epigenetic mechanisms (Dan et al., Developmental cell 29, 7-19, 2014; Wu et al. Cell stem cell 15, 281-294, 2014). Our ongoing research encompasses two areas: (1) novel functions of endogenous retrotransposon in regulating the nuclear structure, metabolisms of PSCs; (2) detecting and investigating rare DNA and RNA modifications in PSCs.
- Well-trained in molecular biology as demonstrated by a solid publication record.
- Abilities to lead an independent research direction while adapting to a collaborative environment.
- An innovative yet critical thinker.
Candidates with following research experiences are highly encouraged to apply:
- Nuclear cell biology and super-resolution imaging
- Epigenetics and chromatin biology
- Biochemistry of histone, DNA and RNA modification enzymes
- Mitochondria and Metabolism
- Manipulation of pre-implantation embryos
- Human and primate ESCs and/or iPSCs